Kiyokazu Ozaki Selected Research

Alloxan

1/2022	High-fat diet-induced nonalcoholic steatohepatitis is accelerated by low carnitine and impaired glucose tolerance in novel murine models.
7/2020	Superimposition of hypertension on diabetic peripheral neuropathy affects small unmyelinated sensory nerves in the skin and myelinated tibial and sural nerves in rats with alloxan-induced type 1 diabetes.
12/2018	Extended Duration of Hyperglycemia Result in Human-Like Corneal Nerve Lesions in Mice With Alloxan- and Streptozotocin-Induced Type 1 Diabetes.
4/2018	Effect of combined dyslipidemia and hyperglycemia on diabetic peripheral neuropathy in alloxan-induced diabetic WBN/Kob rats.
1/2017	Hyperglycemia simultaneously induces initial caries development and enhances spontaneous occlusal surface wear in molar teeth related to parotid gland disorder in alloxan-induced diabetic rats.
10/2016	Acute alloxan toxicity causes granulomatous tubulointerstitial nephritis with severe mineralization.
1/2016	Lack of Correlation between Aberrant p16, RAR-β2, TIMP3, ERCC1, and BRCA1 Protein Expression and Promoter Methylation in Squamous Cell Carcinoma Accompanying Candida albicans-Induced Inflammation.
1/2016	Effect of deoxycorticosterone acetate-salt-induced hypertension on diabetic peripheral neuropathy in alloxan-induced diabetic WBN/Kob rats.
7/2014	Assessment of Alloxan-Induced Diabetic Rats as a Periodontal Disease Model Using a Selective Cyclooxygenase (COX)-2 Inhibitor.
1/2014	A novel diabetic murine model of Candida albicans-induced mucosal inflammation and proliferation.

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Kiyokazu Ozaki Research Topics

Disease

11	Neoplasms (Cancer) 04/2022 - 02/2002
9	Hyperglycemia 12/2018 - 10/2009
8	Inflammation (Inflammations) 11/2017 - 10/2006
6	Dental Caries (Decay, Dental) 11/2017 - 10/2012
6	Hyperplasia 01/2017 - 10/2006
6	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2016 - 10/2006
4	Fatty Liver 01/2022 - 04/2004
4	Carcinogenesis 01/2022 - 10/2006
4	Peripheral Nervous System Diseases (PNS Diseases) 07/2020 - 08/2010
4	Candidiasis (Moniliasis) 01/2017 - 10/2009
3	Periodontitis 11/2017 - 10/2012
3	Infections 01/2017 - 10/2009
2	Hypertension (High Blood Pressure) 07/2020 - 01/2016
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 07/2020 - 12/2018
2	Necrosis 10/2017 - 04/2016
2	Coloboma (Colobomas) 05/2013 - 08/2011
2	Neoplasm Metastasis (Metastasis) 10/2012 - 11/2007
1	Non-alcoholic Fatty Liver Disease 01/2022
1	Hypercholesterolemia 01/2022
1	Insulin Resistance 01/2022
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2022
1	Obesity 01/2022
1	Glucose Intolerance 01/2022
1	Embryonal Carcinoma 04/2021
1	Cysts 04/2021
1	Teratoma (Teratoid Tumor) 04/2021
1	Cataract (Cataracts) 01/2021
1	Diabetes Mellitus 07/2020
1	Hypertrophy 07/2020
1	Dyslipidemias (Dyslipidemia) 04/2018
1	Disease Progression 01/2017
1	Tooth Attrition (Attrition, Dental) 01/2017
1	Interstitial Nephritis (Tubulointerstitial Nephritis) 10/2016
1	Coumarin Resistance 04/2016
1	Histiocytic Sarcoma 09/2015
1	Periodontal Diseases (Periodontal Disease) 07/2014
1	Atrophy 10/2013
1	Miosis 05/2013
1	Otitis 03/2013
1	Wilms Tumor (Wilm's Tumor) 09/2011
1	Pupil Disorders (Marcus Gunn Pupil) 08/2011
1	Hypoglycemia (Reactive Hypoglycemia) 08/2010
1	Hyperinsulinism (Hyperinsulinemia) 07/2010
1	Merkel Cell Carcinoma 08/2009

Drug/Important Bio-Agent (IBA)

17	AlloxanIBA 01/2022 - 10/2006
5	Insulin (Novolin)FDA Link 01/2022 - 07/2010
3	NAD (NADH)IBA 07/2020 - 01/2016
3	Proteins (Proteins, Gene)FDA Link 01/2016 - 11/2007
2	EnzymesIBA 01/2022 - 10/2017
2	Keratins (Keratin)IBA 04/2021 - 02/2019
2	Phenobarbital (Luminal)FDA Link 07/2020 - 10/2016
2	VimentinIBA 02/2019 - 09/2011
2	Melanins (Melanin)IBA 02/2019 - 06/2018
2	Streptozocin (Streptozotocin)FDA Link 12/2018 - 03/2013
2	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 10/2017 - 04/2016
2	coumarinIBA 10/2017 - 04/2016
2	Indicators and Reagents (Reagents)IBA 05/2013 - 08/2011
2	iridalIBA 05/2013 - 08/2011
2	Messenger RNA (mRNA)IBA 03/2013 - 02/2002
2	Systemic carnitine deficiencyIBA 05/2011 - 04/2004
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2005 - 11/2003
2	IronIBA 01/2005 - 11/2003
1	fascinIBA 04/2022
1	DesminIBA 04/2022
1	Carnitine (L-Carnitine)FDA LinkGeneric 01/2022
1	Crystallins (Crystallin)IBA 01/2021
1	MART-1 AntigenIBA 06/2018
1	CholesterolIBA 04/2018
1	Triglycerides (Triacylglycerol)IBA 04/2018
1	Matrix Metalloproteinases (MMPs)IBA 01/2018
1	FluoridesIBA 11/2017
1	Coloring Agents (Dyes)IBA 01/2017
1	Pilocarpine (Ocusert)FDA LinkGeneric 01/2017
1	Prednisolone (Predate)FDA LinkGeneric 01/2017
1	Staphylococcus aureus auR protein (staphylokinase)IBA 01/2017
1	Tolonium Chloride FDA Link 01/2017
1	Nuclear Proteins (Protein, Nuclear)IBA 01/2016
1	Desoxycorticosterone (Deoxycorticosterone)IBA 01/2016
1	Acetates (Acetic Acid Esters)FDA Link 01/2016
1	Tissue Inhibitor of Metalloproteinase-3IBA 01/2016
1	BRCA1 ProteinIBA 01/2016
1	SaltsIBA 01/2016
1	Cadherins (E-Cadherin)IBA 09/2015
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 07/2014
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 07/2014
1	Blood Glucose (Blood Sugar)IBA 10/2013
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2013
1	SugarsIBA 01/2013
1	Anti-Infective Agents (Microbicides)IBA 10/2012
1	Tetracycline (Achromycin)FDA LinkGeneric 10/2012
1	placental alkaline phosphataseIBA 09/2011
1	Hypoglycemic Agents (Hypoglycemics)IBA 08/2010
1	Methylnitronitrosoguanidine (MNNG)IBA 07/2010
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 07/2010
1	Retinal Pigments (Pigments, Visual)IBA 10/2009
1	Itraconazole (Sporanox)FDA LinkGeneric 10/2009
1	SynaptophysinIBA 08/2009

Therapy/Procedure

2	Therapeutics 10/2012 - 08/2010
1	Fluoride Treatment 11/2017
1	Glycemic Control 07/2013